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KMID : 0358320100510050308
Korean Journal of Urology
2010 Volume.51 No. 5 p.308 ~ p.312
The Role of Endorectal Magnetic Resonance Imaging in Predicting Extraprostatic Extension and Seminal Vesicle Invasion in Clinically Localized Prostate Cancer
Park Seo-Yong

Choi Han-Yong
Han Deok-Hyun
Lee Hyun-Moo
Kwon Ghee-Young
Kim Jung-Jun
Kim Tae-Heon
Lim Soo-Hyun
Park Byung-Kwan
Kim Chan-Kyo
Abstract
Purpose: We aimed to assess the clinical value of endorectal magnetic resonance imaging (MRI) in predicting extraprostatic extension and seminal vesicle invasion in patients with clinically localized prostate cancer.

Materials and Methods: A total of 54 patients who underwent radical prostatectomy for clinically localized prostate cancer were retrospectively analyzed. The findings of endorectal MRI, performed at least 3 weeks after biopsy, were compared with the pathological results of radical prostatectomy specimens. The sensitivity, specificity, and accuracy of the detection of extraprostatic extension and seminal vesicle invasion were calculated.

Results: The sensitivity, specificity, and accuracy of the endorectal MRI findings were 50.0%, 82.6%, and 77.8% for the detection of extraprostatic extension, respectively, and 75.0%, 92.0%, and 90.7% for the detection of seminal vesicle invasion, respectively. The sensitivity of endorectal MRI in the detection of extraprostatic extension improved as the Gleason score increased.

Conclusions: Endorectal MRI findings demonstrated modest sensitivity for predicting extraprostatic extension, whereas specificity was relatively high. In addition, endorectal MRI showed better sensitivity for detecting high-grade tumors.
KEYWORD
Magnetic resonance imaging, Neoplasm staging, Prostatic neoplasms
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